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Publications

Regulation of macrophage polarization by RON receptor tyrosine kinase signalling

Authors: Laurel L. Lenz1, Christine Skerka 2, Miki Nakao 3, Amitabha Chaudhuri 4

1. University of Colorado School of Medicine, USA
2.Leibniz Institute for Natural Product Research and Infection Biology, Germany
3.Kyushu University, Japan
4. MedGenome Inc., QB3@953, 953 Indiana Street, San Francisco, CA 94107, USA

DOI: 10.3389/fimmu.2014.00546. October 2014 | Volume 5 | Article 546 |

Journal : Frontiers in Immunology

For More Details : Click Here

Prevalence of genetic variants associated with cardiovascular disease risk and drug response in the Southern Indian population of Kerala

Authors: Lakshmi Mahadevan1, Ancy Yesudas1, PK Sajesh1, S Revu1, Prasanna Kumar1, Devi Santhosh1, Sam Santhosh1, JM Sashikumar2, VK Gopalakrishnan3, Joji Boben4, Changanamkandath Rajesh1

1. MedGenome (Division of Molecular Diagnostics), SciGenom Labs Pvt. Ltd, CSEZ, Kakkanad, Cochin, Kerala, India
2. Department of Biotechnology, Karpagam University, Coimbatore, Tamil Nadu, India
3. Department of Biochemistry, Karpagam University, Coimbatore, Tamil Nadu, India
4. Meditrina Cardiac Centre, St. Thomas Hospital, Changanassery, Kerala, India

DOI: 10.4103/0971-6866.142896 Year : 2014 | Volume : 20 | Issue : 2 | Page : 175-184

Journal : Indian Journal of Human Genetics.

For More Details : http://www.ijhg.com/article.asp?issn=0971-6866;year=2014;volume=20;issue=2;spage=175;epage=184;aulast=Mahadevan

Whole Genome Sequencing and Analysis of Plant Growth Promoting Bacteria Isolated from the Rhizosphere of Plantation Crops Coconut, Cocoa and Arecanut

Authors: Alka Gupta, Murali Gopal, George V. Thomas, Vinu Manikandan, John Gajewski, George Thomas, Somasekar Seshagiri, Stephan C. Schuster, Preeti Rajesh, Ravi Gupta.
Published: August 27, 2014
DOI: 10.1371/journal.pone.0104259
For More Details: http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0104259
http://www.ncbi.nlm.nih.gov/pubmed/25162593.

Prevalence of genetic variants associated with Cardiovascular Disease Risk and Drug Response in the Southern Indian Population of Kerala*

Date of Acceptance: Thursday, June 12, 2014 5:33:31 AM GMT
*Manuscript Accepted Journal : Indian Journal of Human Genetics

Transcriptome Profiling Reveals Higher Vertebrate Orthologous of Intra-Cytoplasmic Pattern Recognition Receptors in Grey Bamboo Shark

Authors: Tirumurugaan Krishnaswamy Gopalan, Pradheepa Gururaj, Ravi Gupta, Dhinakar Raj Gopal, Preeti Rajesh, Balachandran Chidambaram, Aravindan Kalyanasundaram,Raja Angamuthu.
Published: June 23, 2014
DOI: 10.1371/journal.pone.0100018
For More Details: http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0100018



Cost-efficient HIV-1 drug resistance surveillance using multiplexed high throughput amplicon sequencing: Implications for use in low and middle income countries

Authors: Ekici, Halime,Rao S, Sönnerborg A,Ramprasad VL, Gupta R, Neogi U.
Date: 2014-06-11
Location: Föreläsningssalen 4U (Solen), Karolinska Institutet, Huddinge
Department: Inst för laboratoriemedicin / Dept of Laboratory Medicine
For More Details: http://publications.ki.se/xmlui/handle/10616/42038

Recessive mutations in SLC38A8 cause foveal hypoplasia and optic nerve misrouting without albinism

Authors: Poulter JA, Al-Araimi M, Conte I, van Genderen MM, Sheridan E, Carr IM, Parry DA, Shires M, Carrella S, Bradbury J, Khan K, Lakeman P, Sergouniotis PI, Webster AR, Moore AT, Pal B, Mohamed MD, Venkataramana A, Ramprasad V, Shetty R, Saktivel M, Kumaramanickavel G, Tan A, Mackey DA, Hewitt AW, Banfi S, Ali M, Inglehearn CF, Toomes C.

Am J Hum Genet. 2013 Dec 5;93(6):1143-50. doi: 10.1016/j.ajhg.2013.11.002. Epub 2013 Nov 27.
For More Details:http://www.ncbi.nlm.nih.gov/pubmed/24290379

Host genetic background impacts modulation of the TLR4 pathway by RON in tissue-associated macrophages

Authors: Amitabha Chaudhuri1,6,7, Nicholas S Wilson1,6,8, Becky Yang1, Andres Paler Martinez2, Jinfeng Liu3, Catherine Zhu1, Nicole Bricker1, Suzana Couto4, Zora Modrusan5, Dorothy French4, James Cupp5 and Avi Ashkenazi1
1. 1 Department of Molecular Oncology, Genentech Inc., South San Francisco, CA, USA
2. 2 Department of Discovery Immunology, Genentech Inc., South San Francisco, CA, USA
3. 3 Department of Bioinformatics, Genentech Inc., South San Francisco, CA, USA
4. 4 Departments of Pathology and Antibody Engineering, Genentech Inc., South San Francisco, CA, USA
5. 5 Department of Molecular Biology, Genentech Inc., South San Francisco, CA, USA
Correspondence: Dr A Ashkenazi or Dr A Chaudhuri, Department of Molecular Oncology, Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, USA. E-mail: aa@gene.com or amitc@scigenom.com
6 These two authors contributed equally to this work.
7 Current address: SciGenom Inc., Pleasanton, CA, USA.
8 Current address: Immuno-Oncology, EMD Serono Research and Development Institute Inc., MA, USA.
Advance online publication 2 July 2013
Immunology and Cell Biology
ISSN: 0818-9641
EISSN: 1440-1711
For More Details:http://www.nature.com/icb/journal/v91/n7/abs/icb201327a.html

Sequencing and analysis of a South Asian-Indian personal genome

Authors: Ravi Gupta1, Aakrosh Ratan2, Changanamkandath Rajesh1, Rong Chen3, Hie Lim Kim2, Richard Burhans2, Webb Miller2, Sam Santhosh1, Ramana V Davuluri4, Atul J Butte5, Stephan C Schuster26*, Somasekar Seshagiri7* and George Thomas1
Corresponding authors: Stephan C Schuster scs@bx.psu.edu - Somasekar Seshagiri sekar@gene.com - George Thomas georget@scigenom.com

Author Affiliations
1 SciGenom Labs Pvt Ltd., Plot 43A, SDF 3rd Floor CSEZ, Kakkanad, Cochin, Kerala, 682037, India
2 Center for Comparative Genomics and Bioinformatics, Pennsylvania State University, 310 Wartik Lab, University Park, , Pennsylvania, 16802, USA
3 , , Personalis, 1350 Willow Road, Suite 202, Menlo Park, CA, 94025, USA
4 Center for Systems The Wistar Institute,, , Philadelphia, PA, 19104, USA
5 Division of Systems Medicine, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA
6 Singapore Centre on Environmental Life Sciences Engineering, Nanyang Technological University, 60 Nanyang Drive, SBS-01N-27, Singapore, Singapore , 637551
7 Department of Molecular Biology, Genentech Inc, 1 DNA Way, South San Francisco, CA, 94080, USA
BMC Genomics 2012, 13:440 doi:10.1186/1471-2164-13-440, Published: 31 August 2012
For More Details: http://www.biomedcentral.com/1471-2164/13/440#


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